Calcium, an indispensable element in bone tissues, plays a crucial role in various cellular processes involved in cancer progression.Its ubiquitous yet spatially distinct distribution in the body presents an opportunity to target calcium homeostasis as a novel strategies for cancer treatment, with specific advantages in osteosarcoma therapy.In this
The dual nature of Jesus still leaves problems of interpretation and understanding.The emphasis on the humanity of Jesus is excessive, resulting in His divinity needing to be addressed in some aspects.On the 401 other hand, overemphasizing the divinity of Jesus resulted in His humanity being hindered, especially in the aspect of His suffering and d
Lacewings (Neuroptera) normally bear four well-developed wings.There are a few brachypterous, micropterous or apterous species, found in several extant families; this wing reduction is usually associated with flightlessness.The only documented fossil neuropteran with reduced hind wings (modified to small haltere-like structures) is the enigmatic mi
In multistable dynamical systems Electronic Boards driven by weak Gaussian noise, transitions between competing states are often assumed to pass via a saddle on the separating basin boundary.By contrast, we show that timescale separation can cause saddle avoidance in nongradient systems.Using toy models from neuroscience and ecology, we study cases
Abstract Adult central nervous system (CNS) axons fail to regenerate after injury, and master regulators of the regenerative program remain to be identified.We analyzed the transcriptomes Decorative Bowls of retinal ganglion cells (RGCs) at 1 and 5 days after optic nerve injury with and without a cocktail of strongly pro-regenerative factors to dis